Chongwon Pae, PhD

• About

I am a Research Assistant Professor in the Department of Radiology at Seoul National University Hospital and the Seoul National University Brain Imaging Center(SNUBIC). I received my Ph.D. in Neuroimaging and Neuroscience from Yonsei University College of Medicine under the mentorship of Professor Hae-Jeong Park. As a Computational and Systems Neuroscientist, I seek to understand the brain as a complex, dynamic, and networked system. 

My research focuses on integrating neuroimaging, medical imaging data science, neuroinformatics, and machine learning to uncover the organizational principles of the brain and their perturbations in diseases. I develop computational pipelines that span brain and body imaging, leverage advanced MRI, CT, nuclear medicine, and specialty imaging, and apply network science approaches, such as connectomics, multilayer modeling, controllability analysis, and dynamic causal modeling. These methodological frameworks allow me to characterize structural and functional circuits with high granularity and link them with systemic physiology. 

Building on these tools, my work aims to advance precision medicine in neurology and psychiatry by bridging fundamental systems-level mechanisms and clinical translation. I focus on individualized diagnostics, prediction of neuropsychiatric trajectories, and identification of systemic determinants that shape brain health. Through translational computational psychiatry and brain-body interaction research, I strive to develop integrative models that explain how metabolic, vascular, and neural processes converge to influence cognition, emotions, and behavior. Ultimately, my goal is to contribute to more effective and personalized interventions based on a deeper understanding of the brain-mind-body axis.